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ADME / Tox
Prediction

De-risk your drug candidates early with comprehensive in-silico ADME and toxicology profiling. Predict clinical liabilities before investing in expensive in-vitro or in-vivo assays.

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Lipinski
Rule of Five
hERG
Cardiac liability
BBB
CNS penetration
CYP
Metabolic profiling

Comprehensive ADME/Tox Coverage

01

Absorption & Bioavailability

Caco-2 permeability, oral bioavailability, Pgp substrate probability, solubility (kinetic/thermodynamic), and GI absorption profiling.

02

Distribution

Blood-brain barrier penetration, plasma protein binding (PPB), volume of distribution (Vd), and tissue distribution mapping.

03

Metabolism

CYP450 inhibition (1A2, 2C9, 2C19, 2D6, 3A4), metabolic stability, reactive metabolite prediction, and glucuronidation/sulfation profiling.

04

Excretion & PK

Half-life prediction, renal clearance, biliary excretion, PK parameter modeling, and drug accumulation risk assessment.

05

Toxicology Screening

hERG liability, hepatotoxicity (DILI), mutagenicity (Ames/SRM), carcinogenicity, skin sensitization, and reproductive toxicity prediction.

06

Drug-Likeness & Lead Profiling

Lipinski/Veber/Egan filters, synthetic accessibility scores, PAINS filter, pan-assay interference assessment, and promiscuity flagging.

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ADME/Tox Project Request

Submit your compound(s) for a full in-silico ADME/Tox profile with detailed report.